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WHAT IS 1-MNA? THE NAD-SUPPORTING VITAMIN B3 METABOLITE YOUR BODY ALREADY MAKES: 1-MNA (1-Methylnicotinamide) is a natural metabolite of Vitamin B3/Niacin — a compound your body produces when it processes niacin. It's found naturally in wakame algae and green tea leaves, but you'd need to consume 1 kg daily to match one Endotelio capsule. Unlike NMN or NMNH which add precursors, 1-MNA works by regulating the NNMT enzyme to help your body optimise its own NAD levels from within. A fundamentally different — and complementary — approach to NAD support. THE GOLD STANDARD OF NAD SUPPLEMENTATION — EFSA APPROVED, PATENT PROTECTED, SCIENCE BACKED: While most NAD supplements are based on NMN or NR — compounds with no Novel Food approval in the EU — 1-MNA stands apart. Over 100 peer-reviewed publications. 20+ years of research. Multiple international patents. EFSA Novel Food approval confirming its safety and legality as a food supplement. Manufactured in a GMP-certified European facility. If you're choosing a NAD supplement for the long term, choose the one that's been through the most rigorous independent review. TRIED NMN OR NMNH? HERE'S WHY 1-MNA IS THE SMARTER NEXT STEP: NMN and NMNH flood the body with NAD precursors. 1-MNA takes a more elegant approach — it regulates the NNMT enzyme to stop your body wasting the nicotinamide it already has, while directly activating SIRT1 longevity proteins. Think of NMN as turning up the tap; 1-MNA as fixing the leak. Many biohackers use both for synergistic effect. Backed by EFSA Novel Food approval, 100+ publications and 20+ years of research — the science is unambiguous. HOW 1-MNA DIFFERS FROM NMN & NMNH — A COMPLEMENTARY MECHANISM: NMN and NMNH are NAD precursors — they supply raw material for NAD production. 1-MNA works differently: as a natural Vitamin B3 metabolite, it contributes to normal energy-yielding metabolism and helps regulate the NNMT enzyme, preserving the nicotinamide your body needs for its own NAD synthesis. Research also shows 1-MNA directly supports SIRT1 — one of the seven sirtuin proteins involved in cellular metabolism and stress response. Different mechanism, genuine complementarity. Some users take both. START HERE. THE WORLD'S MOST RESEARCHED 1-MNA SUPPLEMENT — ONE CAPSULE DAILY: If you're new to 1-MNA, this is your starting point. Pure, patented, EFSA-approved 1-Methylnicotinamide — nothing added, nothing diluted. The molecule that Blue Zone populations in Okinawa get from 1 kg of wakame or green tea daily, condensed into one transparent capsule. Join thousands of biohackers and longevity enthusiasts who've made 1-MNA their daily foundation. One capsule. Every morning. That's it.